BRCA1-BRCA2 Complex as A Drug Target Or Biomarker for Breast Cancer

Target Name: BRCA1-BRCA2-containing complex

NCBI ID: P15464

BRCA1-BRCA2-containing complex

Other Name(s): BRCC

BRCA1-BRCA2 Complex as A Drug Target Or Biomarker for Breast Cancer

BRCA1 and BRCA2 are tumor suppressor genes that encode for breast cancer suppressor proteins. They are located on the X chromosome and are responsible for maintaining genetic integrity of the female genome. WhenBRCA1 and BRCA2 genes are mutated or expressed at high levels, they can lead to the development of breast cancer. Therefore, targeting these genes has become an important area of research in the field of breast cancer. In this article, we will focus on the BRCA1-BRCA2-containing complex (BRCC), which may be a drug target or biomarker for breast cancer.

BRCC as a drug target
BRCC is a protein complex that contains the BRCA1 and BRCA2 genes. It is expressed in the cells of the breast tissue and has been shown to be involved in the regulation of cell growth, apoptosis, and angiogenesis. The BRCC complex has been shown to play a role in the development and progression of breast cancer.

BRCC has been shown to promote the growth and survival of breast cancer cells. In a study published in the journal Nature, researchers found thatBRCC increased the growth and survival of human breast cancer cells. They also found thatBRCC inhibited the production of cell cycle proteins, which are important for cell growth, in breast cancer cells.

BRCC has also been shown to promote the formation of blood-brain barrier (BBRB) in breast cancer cells. The BBRB is a barrier that separates the brain from the rest of the body and helps to protect it from foreign substances. In a study published in the journal Cancer Cell International, researchers found thatBRCC increased the formation of BBRB in breast cancer cells.

BRCC has also been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. In a study published in the journal PLoS One, researchers found thatBRCC regulated the angiogenesis of breast cancer cells.

BRCC as a biomarker
BRCC has also been shown to be a potential biomarker for breast cancer. In a study published in the journal Biochimica et Biophysica Acta (BBA) - Oncology, researchers found thatBRCC was significantly elevated in the blood of women with breast cancer compared to those without breast cancer. They also found thatBRCC was decreased in the breast tissue of women with breast cancer.

BRCC has also been shown to be a potential target for anti-breast cancer drugs. In a study published in the journal Cancer and Metastasis Reviews, researchers found thatBRCC was a common target for anti-breast cancer drugs. They also found that targeting BRCC with anti-breast cancer drugs was effective in inhibiting the growth and survival of breast cancer cells.

BRCC as a drug target
BRCC has been shown to be a potential drug target for breast cancer. In a study published in the journal Molecular Breast Cancer, researchers found thatBRCC was a common target for anti-breast cancer drugs. They also found that targeting BRCC with anti-breast cancer drugs was effective in inhibiting the growth and survival of breast cancer cells.

BRCC has also been shown to be involved in the regulation of cell signaling pathways. In a study published in the journal Biochimica et Biophysica Acta (BBA) - Molecular Biology, researchers found thatBRCC was involved in the regulation of the PI3K/Akt signaling pathway. They also found that inhibiting the PI3K/Akt signaling pathway with Lodging inhibitors was effective in inhibiting the growth and survival of breast cancer cells.

BRCC has also been shown to be involved in

Protein Name: BRCA1-BRCA2-containing Complex

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